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Michael Florian Mette

Research Scientist

Research Group: Heribert Hirt

Research Interests

Epigenetic analysis deals with cases of alternate gene expression states that are heritable, but are not caused by changes in DNA sequences. In plants, such phenomena can be based on alternate chromatin states capable of stand-alone maintenance. My work is aimed to explore the underlying mechanisms in the model plant Arabidopsis thaliana in order to understand their contribution to plant performance and to provide a knowledge base for harnessing them in green biotechnology.

Selected Publications

  • DNA methylation maintenance consolidates RNA-directed DNA methylation and transcriptional gene silencing over generations in Arabidopsis thaliana. M. Kuhlmann, A. Finke, M. Mascher, M.F. Mette Plant Journal, Volume 80, 269-281, (2014)
  • IDN2 has a role downstream of siRNA formation in RNA-directed DNA methylation. A. Finke, M. Kuhlmann, M.F. Mette Epigenetics, Volume 7, 950-960, (2012)
  • Developmentally non-redundant SET domain proteins SUVH2 and SUVH9 are required for transcriptional gene silencing in Arabidopsis thaliana. M. Kuhlmann, M.F. Mette Plant Molecular Biology, Volume 79, 623-633, (2012)
  • Induction of telomere-mediated chromosomal truncation and stability of truncated chromosomes in Arabidopsis thaliana. C.H. Teo, L. Ma, E. Kapusi, G. Hensel, J. Kumlehn, I. Schubert, A. Houben, M.F. Mette. Plant Journal, Volume 68, 28-39, (2011)
  • Additive inheritance of histone modifications in Arabidopsis thaliana intra-specific hybrids. A.M. Banaei Moghaddam, F. Roudier, M. Seifert, C. Berard, M.L.M. Magniette, R. Karimi Ashtiyani, A. Houben, V. Colot, M.F. Mette Plant Journal, Volume 67, 691-700, (2011)

    Education Profile

    • Dr. rer. nat. (Ph.D), Biochemistry, Universität Regensburg, Regensburg, Germany, 1996
    • Diplom-Biologe Univ. (M.Sc. Biology), Universität Regensburg, Regensburg, Germany, 1992

    Professional Profile

    • Since 2015: Research scientist, KAUST, Thuwal, Kingdom of Saudi Arabia
    • 2013 – 2015: Research scientist, Leibniz Inst. of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany
    • 2003 – 2012: Research group leader, Leibniz Inst. of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany;
    • 1996 – 2003: Postdoctoral fellow, Inst. for Molecular Biology of the Austrian Academy of Sciences, Salzburg, Austria
    • 1993 – 1996: Ph.D. fellow, Max Planck Inst. of Biochemistry, Martinsried-Planegg, Germany

    Scientific and Professional Memberships

    German Genetics Society (GfG)

    Awards

    “ÖGGGT Lecture” award of the Austrian Society of Genetics and Gene Technology (ÖGGGT) for an outstanding publication of a junior scientist, 1999