We are interested in studying the role of m6A RNA modifications in regulating plant immunity.
The N6-methyladenosine (m6A) modification is the most common internal RNA modification in plants. m6A is catalyzed by a multi-component methyltransferase (m6A writer) complex known as MTA complex in plants. m6A functions in key RNA metabolic processes by regulating gene expression, mRNA stability, translation efficiency, alternative splicing, and cytoplasmic mRNA turnover.
We use Arabidopsis as a model plant where we study a mutant lacking m6A RNA modification. We study plant immunity and its regulation by m6A.