Brande Wulff

Faculty

Associate Professor, Plant Science

Research Interests

​Brande's research programme explores the genetics of disease resistance in wheat. This has led to developing fast, new and efficient methods for gene discovery and cloning which use mutant and natural populations followed by sequence alignment to locate genes. Brande has also co-developed a method for halving the generation time of wheat and other crops, in a controlled environment, dramatically speeding up capabilities for research and breeding purposes. His long-term aim is to use cloned genes from wild ancestors of wheat to engineer durable resistance to these diseases in cultivated wheat.

Selected Publications

  • HAFEEZ AN, ARORA S, GHOSH S, GILBERT D, BOWDEN RL, WULFF BBH (2021). Creation and judicious application of a wheat resistance gene atlas. https://zenodo.org/record/4469514
  • GAURAV K, ARORA S, SILVA P, SÁNCHEZ-MARTÍN J, HORSNELL R, GAO L, BRAR GS, WIDRIG V, RAUPP J, SINGH N, WU S, KALE SM, CHINOY C, NICHOLSON P, QUIROZ-CHÁVEZ J, SIMMONDS J, HAYTA S, SMEDLEY MA, HARWOOD W, PEARCE S, GILBERT D, KANGARA N, GARDENER C, FORNER-MARTÍNEZ M, LIU J, YU G, BODEN S, PASCUCCI A, GHOSH S, HAFEEZ AN, O'HARA T, WAITES J, CHEEMA J, STEUERNAGEL B, PATPOUR M, JUSTESEN AF, LIU S, RUDD JC, AVNI R, SHARON A, STEINER B, PKIRANA RP, BUERSTMAYR H, MEHRABI AA, NASYROVA FY, CHAYUT N, MATNY O, STEFFENSON BJ, SANDHU N, CHHUNEJA P, LAGUDAH E, ELKOT AF, TYRRELL S, BIAN X, DAVEY RP, SIMONSEN M, SCHAUSER L, TIWARI VK, KUTCHER HR, HUCL P, LI A, LIU D-C, MAO L, XU S, BROWN-GUEDIRA G, FARIS J, DVORAK J, LUO M-C, KRASILEVA K, LUX T, ARTMEIER S, MAYER KFX, UAUY C, MASCHER M, BENTLEY AR, KELLER B, POLAND J, WULFF BBH (2021). Evolution of the bread wheat D-subgenome and enriching it with diversity from Aegilops tauschii. www.biorxiv.org/content/10.1101/2021.01.31.428788v1
  • HICKEY LT, HAFEEZ A, ROBINSON H, JACKSON SA, LEAL-BERTIOLI SCM, TESTER M, GAO C, GODWIN ID, HAYES BJ, WULFF BBH (2019). Breeding crops to feed 10 billion. Nature Biotechnology 37:744-754 
  • ARORA S, STEUERNAGEL B, GAURAV K, CHANDRAMOHAN S, LONG Y, MATNY O, JOHNSON R, ENK J, PERIYANNAN S, NARINDER S, HATTA MAMD, ATHIYANNAN N, CHEEMA J, YU G, KANGARA N, GHOSH S, SZABO LJ, POLAND J, BARIANA H, JONES JDG, BENTLEY AR, AYLIFFE M, OLSON E, XU SS, STEFFENSON BJ, LAGUDAH E, WULFF BBH (2019). Resistance gene cloning from a wild crop relative by sequence capture and association genetics. Nature Biotechnology 37:139-143. 
  • STEUERNAGEL B, PERIYANNAN SK, HERNÁNDEZ-PINZÓN I, WITEK K, ROUSE MN, YU G, HATTA A, AYLIFFE M, BARIANA H, JONES JDG, LAGUDAH* ES, WULFF* BBH (2016). Rapid cloning of disease-resistance genes in plants using mutagenesis and sequence capture. Nature Biotechnology, 34:652-5.

Education

  • ​Postdoc, IBMP-CNRS, Strasbourg, France, 2008
  • Human Frontiers Postdoc Fellow, IBMCP-CSIC, Spain, 2005
  • EMBO Postdoc Fellow, IBMCP-CSIC, Spain, 2004
  • PhD, The Sainsbury Laboratory, UK, 2001
  • BSc, University of East Anglia, UK, 1997