Rashid Aman

Postdoctoral Fellow

Postdoctoral Fellow

Research Interest

I am interested in exploring the use of CRISPR/Cas technologies for virus interference and other RNA manipulations in plants. Cas9 has been widely been exploited in developing various fruitful genome engineering technologies such as for virus interference and various genetic manipulations. However, the use of new CRISPR effectors for virus interference or other genetic manipulations remains challenging. We have successfully employed and screened different RNA targeting CRISPR/Cas13 effectors to find out the most effective one for virus interference in plants. My research interst now lies in understanding the use of CRISPR/Cas13 effectors for transciptome engineering and other RNA manipulations in plants. Besides this my research interests also focuses on the development of genome engineering technologies for basic biology and biotechnology

Selected Publications

Aman R, Mahas A, Mahfouz M. Nucleic Acid Detection Using CRISPR/Cas Bio-sensing Technologies. ACS Synthetic Biology. 2020 Mar 11. DOI:10. 1021/acssynbio.9b00507. 

Mahas Ahmed*, Rashid Aman*, and Magdy Mahfouz. "CRISPR-Cas13d mediates robust RNA virus interference in plants." Genome Biology 20.1 (2019): 1-16. (*Equal contribution).

Rashid Aman, Ahmed Mahas, Haroon Butt, Zahir Ali, Fatimah Aljedaani and Magdy Mahfouz (2018). Engineering RNA virus interference via the CRISPR/Cas13 machinery in Arabidopsis. Viruses. 2018 Dec 19; 10:732. doi: 10.3390/v10120732.


Rashid Aman, Zahir Ali, Haroon Butt, Ahmed Mahas, Fatimah Aljedaani, Muhammad Zuhaib Khan, Shouwei Ding and Magdy Mahfouz (2018). RNA virus interference via CRISPR/Cas13a system in plants. Genome Biology. 2018 Jan 4; 19(1):1. doi: 10.1186/s13059-017-1381-1.

Akhtar Ali, Natalia Raddatz, Rashid Aman, Songmi Kim, Hyeong Cheol Park, Dongwon Baek, Masood Jan, Dong-Ha Oh, Irfan Ullah Khan, Sang Yeol Lee, Ray A.Bressan, Keun Woo Lee, Jose M. Pardo, Albino Maggio, Hans J. Bohnert, Dae-Jin Yun (2016). A keystone Mutation in Plant Sodium Transporter HKT1 Enabling the Evolution of Salt Tolerance. Plant Physiology. 2016 Jul; 171(3):2112-26. doi: 10.1104/pp.16.00569.) 

Qiguang Xiea, Ping Loua, Victor Hermand, Rashid Aman, Hee Jin Park, Dae-Jin Yun, Woe Yeon Kim, Matti Juhani Salmela, Brent E. Ewers, Cynthia Weinig, Sarah L. Khan, D. Loring P. Schaible, and C. Robertson McClung (2015) Allelic polymorphism of GIGANTEA is responsible for naturally occurring variation in circadian period in Brassica rapa. Proc Natl Acad Sci 112:3829–3834. doi: 10.1073/pnas.1421803112 

Zahir Ali, Akhtar Ali, Hyeong Cheol Park, Dong ha Oh, Rashid Aman, Hans J. Bohnert, Woe Yeon Kim, Dae-Jin Yun (2012) TsHKT1;2, a HKT1 homolog from the extremophile Arabidopsisrelative Thellungiella salsuginea, shows K+-specificity in the presence of NaCl. Plant physiology; 158(3):1463-74. 

Akhtar Ali, Hyeong Cheol Park, Rashid Aman, Zahir Ali, Dae-Jin Yun (2013) Role of HKT1 in Thellungiella salsuginea, a model extremophile plant. Plant Signaling and Behavior. doi: 10.4161/psb.25196 

Education

PhD, Plant Molecular Biology, Gyeongsang National University, Jinju, South Korea, 2015 

Professional Profile

2017-Present: Postdoctoral fellow, KAUST, Thuwal, Saudi Arabia
2016-2017: Visiting Scientist, KAUST, Thuwal, Saudi Arabia
2015-2016: Postdoctoral fellow, Gyeongsang National University, Jinju, South Korea 

Awards

World Class University program, Gyeongsang National University, South Korea, 2009-2011 

Brain Korea Scholarship (BK-21), Gyeongsang National University, South Korea, 2012-2014 

KAUST Affiliations

Prof. Magdy Mahfouz

Research Interests Keywords

Virus based plant genome engineering CRISPR/Cas 9 (Cas9 and Cas13) technology for plant genome engineering CRISPR/Cas13 based RNA virus interference and other RNA manipulations in plants Abiotic Stress Tolerance (Salt-Tolerance) Plant Molecular Biology Plant Biochemistry Cross-talks between Flowering and Salt stress Tolerance High Affinity Potassium Transport in Arabidopsis and Thellungiella salsuginea Plant Physiology