Mohamed Abd Allah Salem

Research Scientists

Research Scientist

Location:

Building 2, Room 3231-WS05

Research Interests

Metabolomics, the large scale metabolite analysis, is becoming an attractive tool for the (un)targeted analysis of metabolites in particularly in complex biological systems. One of our aims is to uncover the role of root and root exuded metabolites in plant–rhizosphere communication. Dr. Salem's research interests include, but are not limited to metabolite profiling, food chemistry, devolvement of LC-MS analytical methods and isolation of natural products. His main current research focuses on the use of metabolomics approaches linked to chemometrics for better understanding of relation between plant metabolites and rhizosphere.

Selected Publications

  • Metabolomics of plant root exudates: From sample preparation to data analysis. Mohamed A. Salem, Jian You Wang and Salim Al-Babili. Frontiers in Plant Science, 13:1062982, 2022.
  • Metabolomics driven analysis of Nigella sativa seeds identifies the impact of roasting on the chemical composition and immunomodulatory activity. Mohamed A. Salem, Riham A. El-Shiekh, Nora M. Aborehab, Ahmed A. Al‐Karmalawy, Shahira M. Ezzat, Saleh Alseekh and Alisdair R. Fernie. Food Chemistry, 398, 133906, 2023.
  • An improved extraction method enables the comprehensive analysis of lipids, proteins, metabolites and phytohormones from a single sample of leaf tissue under water-deficit stress. Mohamed A. Salem, Takuya Yoshida, Leonardo Perez de Souza, Saleh Alseekh, Krzysztof Bajdzienko, Alisdair R. Fernie and Patrick Giavalisco. Plant Journal, 103, 2020.
  • RAPTOR controls developmental growth transitions by altering the hormonal and metabolic balance. Mohamed A. Salem, Yan Li, Krzysztof Bajdzienko, Joachim Fisahn, Mutsumi Watanabe, Rainer Hoefgen, Mark Aurel Schöttler and Patrick Giavalisco. Plant Physiology, 177(2):565-593, 2018.
  • Regulatory-Associated Protein of TOR (RAPTOR) alters the hormonal and metabolic composition of Arabidopsis seeds controlling seed longevity and germination potential. Mohamed A. Salem, Yan Li, Andrew Wiszniewski and Patrick Giavalisco. Plant Journal, 92, 525–545, 2017.

Education

  • PhD (Dr. rer. nat.) in Systems Biology, University of Potsdam, and Max Planck Institute of Molecular Plant Physiology (MPIMP-Golm), Germany, 2018.
  • MSc in Pharmaceutical Sciences, Faculty of Pharmacy, Cairo University, Egypt, 2012.
  • BSc in Pharmaceutical Sciences, Faculty of Pharmacy, Cairo university, Egypt, 2006.

Professional Profile

  • 2023- present: Research Scientist, the Bioactives Lab, Division of Biological and Environmental Sciences and Engineering (BESE), KAUST, Thuwal, Kingdom of Saudi Arabia.
  • 2021- 2022: Postdoctoral Fellow, Max Planck Institute of Molecular Plant Physiology (MPIMP-Golm), Germany.
  • 2019- 2023: Lecturer and Researcher, Department of Pharmacognosy and Natural Products, Faculty of Pharmacy, Menoufia University, Egypt.
  • 2018-2019: Lecturer and Researcher, Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt.

Research Interests Keywords

metabolomics LC-MS analytical methods plant hormones primary & secondary metabolites